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For instance, in a double-blind, randomized, controlled trial of HIV-1-positive adults published in the Archives of Internal Medicine , daily supplementation with 200 micrograms of selenium significantly raised serum selenium levels and was associated with reduced HIV-1 viral load and an increase in CD4+ T-cell count, suggesting enhanced immune support and slower disease progression compared with placebo

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Nutr Rev (2000) 58(6):17780

[14] confirmed the roles of NNMT in the development of T2D