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Nutrient interactions Together with several B-vitamins (i.e., folate, vitamin B 12 , vitamin B 6 , and riboflavin), choline is required for the metabolism of nucleic acids and amino acids, and for the generation of the universal methyl group donor, S-adenosylmethionine (SAM) ( Figure 4 )

Lemons contain several bioactive compounds that have attracted scientific interest, including vitamin C (ascorbic acid), flavonoids such as hesperidin and eriocitrin, and limonene

Because estrogen stimulates the endogenous synthesis of phosphatidylcholine via the phosphatidylethanolamine N-methyltransferase (PEMT) pathway, premenopausal women may be less likely to develop signs of choline deficiency in response to a low-choline diet compared to postmenopausal women (18, 19)

La inestabilidad de la vitamina C combinada con su relativamente pobre absorcin y facil excrecin reducen la disponibilidad fisiolgica de esta vitamina