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NAD+-consuming enzymes in immune defense against viral infection
(2014) 111(45):E486977

That study was the first to report the use of TL as a novel predictor of response to antidepressant medication and was consistent with other studies that subsequently reported that shorter TL was associated with poorer response to certain psychiatric medications, including antipsychotics in schizophrenia 39,40 , adjunctive pioglitazone in MDD 41 , and lithium among patients with bipolar disorder 42

However, its efficacy is often limited due to intrinsic or acquired resistance

To dissect the actions of AVP in health and disease further research is needed