do you have to refrigerate bac water after opening π§ How to Store Bacteriostatic Water Safely does bac water need to
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[NCBI Bookshelf] ncbi.nlm.nih.gov OKane M, Parretti HM, Pinkney J, et al

So, the B12 in the serum is OK, but in the brain, it is low

10.1136/jnnp.2009.178657

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68,69 However not all researchers have demonstrated an inverse association between vitamin B 12 status and metformin treatment as exemplified by one small study performed in Qatar