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The decreased NAMPT might be due to the chronic inflammation and impaired circadian clock during aging

Chen, F., Zhang, Q., Ma, J., Zhu, Q., Wang, Y., & Liang, H

doi: 10.1016/j.exger.2007.12.002 67 DohertyKConnorMCruickshankR

Inhibition of HIF-1alpha reduced blood brain barrier damage by regulating MMP-2 and VEGF during acute cerebral ischemia

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