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However, morphological studies have demonstrated that cochlear development proceeds normally, and the gross morphology of the organ of Corti is normal, indicating that Lgr5 is dispensable for hair cell formation (Chai et al., Lgr5 -positive cells in the postmitotic neonatal cochlea that have garnered attention recently as a possible source of hair cell progenitors

doi: 10.1007/s00264-006-0087-x

Kovalzon and Strekalova, summarizing the field in 2006, were explicit: the link between DSIP and sleep had never been further characterized, in part because of the lack of isolation of the DSIP gene, protein and possible related receptor, and the hypothesis of DSIP as a sleep factor was extremely poorly documented and still weak (Kovalzon & Strekalova, 2006)

Informed practice requires more than just familiarity with popular peptides

The JmjC-domain-con- taining histone demethylases reversibly and specifi- cally cleave N-methyl groups from the lysine residues of histones