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It also plays a role in the growth and development of synapses the connections between neurons

Deficient butyrate-producing capacity in the gut Microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFS

Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation

Starting low and adjusting based on results and tolerance is the recommended approach

Day et al
