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Increasingly, patients are now seeking out alternatives to surgical interventions

[PubMed] [Google Scholar] Rizhsky L., Hallak-Herr E., Van Breusegem F., Rachmilevitch S., Barr J.E., Rodermel S., Inz D., Mittler R

Users and researchers have documented effects across several domains of health and performance, though it bears mentioning that much of this evidence comes from animal studies, small human trials, or anecdotal reports rather than large-scale clinical trials

That's one reason why results vary from person to person

Some researchers report maintaining potency for longer periods, but 28 days is the evidence-based safety threshold
