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Minnix M, Adhikarla V, Caserta E, Poku E, Rockne R, Shively JE, et al

doi: 10.1016/j.tics.2010.11.004 25

The cold temperature reduces the kinetic energy of molecules, thereby slowing down reactions that lead to peptide degradation
One common off-label use is for insomnia, as trazodones sedative effects can help people fall asleep and stay asleep
