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Their findings showed that BDNF protein expression in rat embryonic NSCs transfected with the human BDNF gene (BDNF-NSCs) was upregulated, while neurite outgrowth in ganglion neurons were simulated, suggesting that BDNF increased neurogenesis in vitro

107,108 In addition to the architecture of the kidney limiting oxygenation, kidney tubules are characterized by a limited ability to generate energy under anaerobic conditions, causing oxygen to be consumed rapidly in the metabolic processes involved in active salt reabsorption

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10.1038/ncb3064 Nat

[ Also, obesity is accompanied by macrophage adipose tissue infiltration, and macrophage-secreted inflammatory cytokines, such as MCP-1, affect the metabolism of adipocytes