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For retatrutide specifically, as it remains an investigational medicine, any adverse events experienced within a clinical trial setting should be reported directly to the trial sponsor and principal investigator in accordance with the trial protocol

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Another condition related to insulin resistance is insomnia and sleep deprivation, both of which can be caused by consuming caffeine

[PubMed] [Google Scholar] 19.Suzuki Y.J., Tsuchiya M., Packer L