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The present work with UChB rats shows the shortest time (voluntary intake plus deprivation) that has even been reported for rats showing neuroinflammation
This structural destabilization activates the CREB3ARF4mediated Golgi stress response, which upregulates pro-inflammatory and pro-apoptotic genes including CHOP, thereby exacerbating cellular injury

Acta 1773 , 93104 (2007)

Thus, the lower redox potential Rstate increases the probability of nitrite reduction
