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The nature of the defect in tyrosine metabolism in alkaptonuria

Consequently, strategies aimed at inhibiting ammonia transport have been proposed as a means of prolonging T-cell lifespans and enhancing antitumor efficacy [98]

Interactions between Sox9 and beta-catenin control chondrocyte differentiation

The increase of ROS within a high oxidative stress level (by decreasing of the antioxidant GPx enzyme) increases the possibility of lipid oxidation, especially LDL-cholesterol and thus favors the formation of anti-LDL-oxidized cholesterol antibodies, which will lead to the initiation of an immune and vascular aggression process (13-18)

Actually, OS generated at the erythroid level can affect not just RBCs, but also neutrophils, monocytes, and endothelial cells