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MSCs cultured under relatively high cell density that increases cellular GSH levels enhances hyaline cartilage regeneration To confirm that the in vivo regenerative capacity of MSCs could vary with the cell culture conditions, we cultured hES-MSCs under two different culture conditions (5 10 3 cells/cm 2

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GSH, the predominant intracellular antioxidant, protects against oxidative damage and peroxide-induced toxicity primarily through the catalytic actions of GST and GPx (Maiorino et al., 2015)