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Through binding to these sequences, m-MITF directly activates the transcription of hundreds of genes in the melanocytic lineage and controls melanocyte proliferation, differentiation, survival, pigment production and various additional processes

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In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography

The basal ROS production, which accounts for approximately 2% of total mitochondrial activity even under optimal conditions, underscores their essential role in cellular physiology (Figure 1) [3, 5]