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Abstract Rising rates of infertility have stimulated interest in dietary supplements to improve oocyte quality through mitochondrial function, antioxidant activity, and epigenetically regulated metabolic pathways

Beyond, it seems that there is an inverse relationship between Oscillibacter (a genera increased in patients with BD) and the levels of tryptophan and KYNA, thereby supporting the relevance of gut microbiota in the altered Kyn pathway and neuroinflammation [235]

[108] described that Mg treatment has no significant effect on plasma CRP concentrations

Another promising approach is gene therapy that targets hepatocytes harboring mutated porphobilinogen deaminase ( PBGD ) gene (Spiritos et al., 2019)

The bioactive compounds found in