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The main component of ASA, amygdalin, inhibits the proliferation and production of transforming growth factors in renal interstitial fibroblasts, which plays a crucial role in the development of renal interstitial fibrosis (Guo et al., 2013)

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Particle size increased with the addition of sweet curd, measuring between 60.7 and 77.56 nm

However, the clinical translation of these systems remains hindered by heterogeneous tumor biology, inconsistent pharmacokinetic outcomes, and insufficient long-term biosafety data

This indicates that synthetic derivatives of natural products are usually more likely to be approved as drugs than themselves, and structural modifications will become a key bridge for successfully converting natural products into new pharmaceuticals [364]