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Description
Polyamine oxidase and diamine oxidase catalyse the production of hydrogen peroxide in a regulated way, which itself acts as a signalling molecule for the activation of defence-linked genes in plants

J Biol Chem 282: 1392913933 [DOI] [PubMed] [Google Scholar] Tu BP, Ho-Schleyer SC, Travers KJ, Weissman JS 2000

While these radicals are essential for pathogen clearance, excessive or chronic inflammation can lead to tissue damage due to the persistent high levels of free radicals [58]

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Oral and topical treatment of painful diabetic polyneuropathy: practice guideline update summary: Report of the AAN guideline subcommittee