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It is therefore no surprise that the breeding and engineering approaches for phytoremediation requiring heavy metal hyperaccumulators have focused on strategies to enhance PC biosynthetic capacity [48, 70, 71, 72, 73, 74, 75, 76]
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Notch pathway activity varies across tumor regions, with higher expression in peritumoral GSCs than in the tumor core, suggesting a role in maintaining stemness and therapeutic resistance

[34] Tang L, Jin T, Zeng X, et al

Endocrinology (2013) 154(9):34019
