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doi:10.3748/wjg.v8.i6.1053 Chen Y, Xu X, Hong S, Chen J, Zhang L

In mechanism, TH inhibits the expression of CSE, while GH inhibits the production of H 2 S through substrate availability control by autophagy ( 2 S in the liver increased (76), which may be due to the different effects of different concentrations of TH on the H 2 S producing enzyme

The study concluded that both topical and oral glutathione are effective skin-lightening agents, with the combination therapy potentially offering superior results

Controlled evidence is concentrated in topical delivery (creams, serums, post-procedure skincare)