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When it comes to Graves disease, hyperthyroidism can worsen the autoimmunity

It upregulates peroxisome proliferator-activated receptor gamma coactivator 1 alpha, the master regulator of mitochondrial biogenesis, which in turn stimulates mitochondrial proliferation [138]

[DOI] [PubMed] [Google Scholar] 95.Masuda Y, Itabe H, Odaki M, Hama K, Fujimoto Y, et al

Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy

10.1210/endocr/bqaa149 20 EdwardsJ
