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doi: 10.2174/1570159x13666160502153022
The findings indicate that NNMTi is a promising inhibitor that targets NNMT and can reverse the obesity induced by diet and prevent the associated T2D
Importantly, lean mice on regular diets did not show significant weight loss at the same doses
Some people are already at higher risk for low B12 levels before starting treatment
The 2.4 mg dose represents the maintenance level used across the STEP obesity program, while doses of 0.5 to 2.0 mg are typically studied in glycemic research
