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Atherosclerosis Atherosclerotic lesions occur via the deposition of cholesterol-rich lipids within the vessel wall, initiating an inflammatory response that leads to the formation of vascular lesions, termed plaques that evolve over time and become susceptible to rupture (122)

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It can exist in different redox states (FADH2, FADH).[ref] Within the mitochondria, FAD and FMN also act as antioxidants, integral to activating the various enzymes that protect cells from oxidative stress, thus making adequate riboflavin essential for healthy mitochondria

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Notably, GJB2 mutations are found in patients with nonsyndromic hearing loss

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