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Description
During the epoxidation of squalene, catalyzed by squalene epoxidase (encoded by the SQLE gene

Education Department of Jiangxi Province (GJJ13198 and GJJ170021)

The expressions of genes CYP2E1, IGFBI, PDK4 and cholesterol 7 alpha-hydroxylase were all markedly increased, indicating that the model had the characteristics of steatosis

In contrast to its canonical role in GSH degradation, we found that in the context of inflammation, Chac2 upregulation led to a pronounced intracellular accumulation of GSH, which in turn enhanced neutrophil N1 effector functions
Jones DP, Radi R
