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Therefore, -syn aggregates can be transported to microglia, where they induce M1 polarization and promote the release of inflammatory factors, thus causing neuroinflammation

in the hereditary paraganglioma-phaeochromocytoma syndrome, HPGL/PCC), succinate increases following inactivating mutations of SDH subunits

At present, there is no drug study on ferroptosis in BC in the clinical trial registration website

A vitamin B12 deficiency can lead to megaloblastic anemia, a condition characterized by a low number of red blood cells that are larger than normal ( Megaloblastic anemia can cause a variety of symptoms and side effects, including ( shortness of breath headache heart palpitations fatigue poor balance memory loss That said, being low in vitamin B12 doesnt always lead to megaloblastic anemia, and many people may only experience mild symptoms like fatigue ( Furthermore, while a deficiency in vitamin B12 may not cause weight gain, it can decrease energy levels and contribute to fatigue, making it harder to stay active and manage your weight

Samples from right tibia were processed for histological examination