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GHK-Cu + Vitamin C & Zinc Research protocols commonly investigate GHK-Cu alongside: Vitamin C Zinc because of their involvement in: Collagen-related pathways Skin-integrity and dermal-maintenance mechanisms Antioxidant-support pathways Tissue-maintenance and regenerative signaling Physiological-resilience pathways Vitamin C is commonly investigated for its interaction with collagen-support and antioxidant-related pathways, while Zinc is frequently researched for its role in skin-integrity, tissue-maintenance, and copper/zinc balance within GHK-Curelated research models

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These findings were supported by the relaxation of large vessels (ex vivo), mainly by acting on vascular endothelial cells but also on vascular smooth muscle cells, increasing NO production and migration of endothelial cells, activating the signal pathways of Src, Cav-1, and eNOS, and reducing proteinprotein interaction between eNOS and Cav-1 [121,122]

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