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Sensitive skin is more prone to react to stimuli to which normal skin has no reaction

Early-life innate immune hyperactivation has been observed in allergic children, while asthmatic children display immune dysregulation characterized by reduced IFN- production and ILC2 expansion in response to rhinovirus or LPS stimulation (145)

They also demonstrated that patients carrying the TP53 -GG (Arg/Arg) genotype had higher levels of BCR-ABL1 transcripts and were more likely to have a worse clinical prognosis compared to those cases with other genotypes (GC/CC) [407]

Research on these therapies points to a positive impact of senescence induction, particularly in the initial stages of the disease [8]

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