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Description
In addition to glucose-6-phosphate, H6PD can metabolize other hexose-6-phosphates, glucose-6-sulfate, and glucose

FIGURE 7 4.5 Multimodal synergistic therapy As mentioned above, we clearly recognize that GSH-responsive and -exhausting metal nanomedicines have a prominent effect on cancer therapy

Castellani S, et al

Collectively, these results suggested that APR-017 and LCS3 treatment induce vulnerability of VRK2-deficient PC cells by GSH inhibition and consequent disruption of the balance between ROS generation and antioxidation

offers consultancy advice around cell-based therapies for Parkinsons disease to Living Cell Technologies, Fujifilm Cellular Dynamics Inc., BlueRock Therapeutics, Novo Nordisk, Cellino Biotech and Aspen Neuroscience
