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Hepatotoxicity The suggested mechanism of hepatotoxicity induced by VPA supports the formation of reactive intermediates to impede -oxidation, resulting in steatosis, and hence causes mitochondrial dysfunction
However, the complex composition of gut microbiota means that the gut microbiota that contributes most to CVDs and the specific mechanism of TMAO are not fully understood
Pengcheng T, Jun W
In this randomized placebo-controlled double blind study in subjects aged 5570 years, researchers investigated the potential synergistic effect of this novel formulation in comparison to placebo after eight-week supplementation
Rarer adverse effects include seizures in those with seizure disorders and muscular weakness in uremic individuals
