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R., Furne, J., Stoltz, G
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ROS increasing is correlated with abnormal cancer cell growth

Proximity-induced degradation of NSD2 does not perturb FBXO22-dependent BACH1 degradation A potential off-target concern of small molecule degraders is that repurposing the E3 Ub ligase will disrupt the ubiquitination and degradation of its native substrates

Pourebrahim R, Montoya RH, Alaniz Z, Ostermann L, Lin PP, Liu B, Ayoub E, Burks JK, Andreeff M
