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In the present study, PFOS time dependently increased IRE1 (an ER stress marker) expression, indicating ER stress induction, which could be eliminated by l-Carnitine through its antioxidative activity

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10.1038/npp.2015.57 100

The interaction effects between the nutritional state and L-carnitine were only seen in the mRNA levels of PFK in muscle and PECK1 and Irb mRNA levels in liver (Supplemental Table 4)
Yamazaki N, Shinohara Y, Shima A, Yamanaka Y, Terada H
