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LDs are specifically taken up by the sterol-enriched, termed liquid-ordered, vacuolar microdomain, which in turn provides the vacuolar membranes with sterols to sustain the lipid phase partitioning [15]
Regulating the cholesterol and preventing atherosclerosis
It is also a mediator of the clinical benefit associated with LDL-C lowering, and a number of excellent recent trials have elucidated the relationship between magnitude of risk reduction, and achieved levels of LDL-C and hsCRP

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