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Introduction Over the past century, extensive research into the biological, chemical, and physical properties of vitamins has revealed their therapeutic benefits beyond their fundamental role as essential micronutrients for human health and development [1]

Among them, cathepsin B is thought to bind to NLRP3, thus activating the NLRP3 inflammasome

Copper is an essential cofactor for superoxide dismutase (SOD), a primary antioxidant enzyme, and GHK-Cu has been studied in models examining oxidative stress mitigation

Dried and finely ground, spinach powder preserves the antioxidant properties of this herb but it ranks behind most culinary preparations in nutritional value

Besides, the chemokine CCL3, which is instrumental in the recruitment of inflammatory cells, has been demonstrated to exacerbate secondary damage following SCI by promoting inflammation and enlarging the lesion area (47)