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Neurons, with their high energy demands, primarily rely on oxidative phosphorylation and the tricarboxylic acid (TCA) cycle to sustain synaptic activity and neurotransmitter synthesis
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qRTPCR and immunofluorescence confirmed reduced NFE2L2 RNA and protein expression in psoriatic lesions compared to normal skin (Fig
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The PYCR2 gene is located on chromosome 1q42.12 and is composed of 7 exons that generate two alternatively spliced mRNAs that encode proteins of 320 amino acids (isoform 1) and 246 amino acids (isoform 2)
