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These findings underscore the intricate relationship between Hcy and lipid metabolism dysregulation, shedding light on potential mechanisms underlying adipose tissue dysfunction and its implications for cardiovascular health

Neither compound holds MHRA or EMA marketing authorisation

Selective and potent inhibitors available for cellular and animal studies will have a high impact on the elucidation of the underlying mechanisms of NNMT-regulated diseases, which would ultimately lead to the identification of new therapeutic strategies

10.2337/dc08-s246 40 GuanX.-X.ZhuX.-J.DengZ.-H.ZengY.-R.LiuJ.-R.LiJ.-H.et al (2021)

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