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This suggests a decreased ability to combat oxidative stress systemically in OLP

[DOI] [PMC free article] [PubMed] [Google Scholar] 151.Matsushita K, et al

As a consequence, the invasion of gram negative enterobacteria initiate the inflammatory cascade wherein Toll like receptor-4 (TLR-4)-induced proinflammatory cytokine upsurge along with NLRP3 inflammosome activation attract the neutrophils eventually leading to oxidative burst, chronic inflammation, apoptosis and ultimately intestinal ulceration [140]

The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration

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