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2G), suggesting that danger signal molecules from damaged neurons lead to microglial and astrocytic activation

Some splicing changes introduce premature stop codons and presumably induce nonsense-mediated decay of the mRNA (leading to reduced synthesis and function), while others modulate protein sequences in important domains (Supplementary Table 3)

Rodent models are the cornerstone of preclinical trials for assessing hepatotoxicity and have been extensively used in research

Therefore, although the origin of the 2nd and 3rd sets of waves cannot perfectly deny the unknown possibility of the central nervous system-related waves, these waves do not seem to be artificial noises