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Version Current: May 2016

Cell and Tissue Research 2010

This data strongly supports the clinical observation that highly bioavailable glutathione is essential for repairing the cellular damage caused by systemic inflammation and mitochondrial dysfunction

30(6):445-600 Josephy, 2010 Josephy PD.(2010)Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology

In comparison, topical delivery of protein drugs to the lung via inhalation is deemed to be a more effective approach for lung diseases, as proteins would directly reach the target in the lung while exhibiting poor diffusion into the systemic circulation, leading to higher lung drug retention and efficacy while minimising toxicity to other organs