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In fruit flies and rats, some studies observed a reduction in age-related mortality indices, and in specific mouse strains predisposed to cardiovascular and oncologic conditions, trends toward longer survival were reported under defined conditions

doi: 10.1016/0167-5699(93)90244-F 30 TangJCaiSYeCDongL

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Methods Participants Forty runners, 20 to 46 years of age were recruited from running clubs across the Louisville, Kentucky, community between November 2014 and February 2015, with data collection completed in May 2015