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There is ample evidence to indicate that factors present in the tumor microenvironment (TME), such as products of inflammatory cells reactive nitrogen and oxygen species may cause DNA damage to the neighboring cells, thereby contributing to tumor progression [102]

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We found that 25% of ARH AgRP neurons (3 out 12 recorded cells from 5 mice) were depolarized by GH (Fig

Cancer 125 , 284298 (2021)

Unlike the Phoqus formulation, which appeared to transit the gastrointestinal (GI) tract slower and more predictably than multi-particulates, the rapid transit of the multi-particulates we presumed had resulted in the majority of the drug payload being delivered to the colon, a region of the GI tract wherein the absorption of hydrocortisone had not been formally studied