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One of these secondary mechanisms is carried out by the DJ-1 protein, which converts MG into lactate in the absence of glutathione (Matsuda et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Zokiriv M
It is argued that increased pseudohypoxia-induced expression of GLUT-1 in interstitial fibroblasts is the key factor in a vicious circle that augments ultrafiltration failure
For instance, heterodimeric NHR49/NHR80 promotes lipid desaturation while NHR49/NHR66 blocks sphingolipid metabolism and lipid remodelling (Pathare et al , 2012)
