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As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]
PMID: 29534031
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This is an unusual mechanism of drug interactions, since usually displacement from albumin will expose more drug to be metabolized (leading to re-equilibration)
