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The recommended daily dose of 300 mg corresponds to the approach used in functional nutrition

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Long-term use may also affect organ function, nutrient balance, and hormone regulation, and could lead to drug-to-drug interactions

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Several lines of evidence have suggested that impaired L-Glu homeostasis is linked to neuronal pathology and death in neurodegenerative diseases (NDDs), such as Alzheimers disease (AD) [10,11], Parkinsons disease (PD) [7,12,13], multiple sclerosis (MS) [14,15,16] amyotrophic lateral sclerosis (ALS) [17,18,19], and Huntingtons disease (HD) [20,21]

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A total of 35 metabolic pathways were associated with the differential metabolites

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Cancer Cell 30 , 337348 (2016)

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