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doi: 10.3892/ijmm.9.6.665

This finding could be explained by a report by Bunn and Higgins in which the reactivity of each monosaccharide with amino groups to form Schiff base linkages is dependent on the extent to which it exists in the open (carbonyl) structure rather than in a ring (hemiacetal or hemiketal) structure, and the rates of reactivity increased in the order of ribose (10.0), fructose (4.5), and glucose (0.6) (10 3 mM 1 h 1 ), respectively 28