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Tesofensine becomes valuable when the bigger issue is metabolic slowdown, fatigue, or plateauing after initial GLP-1 success
The findings confirmed that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo
Two phase 3 trials BLOOM (Behavioral modification and Lorcaserin for Overweight and Obesity Management) and BLOSSOM (Behavioral modification and LOrcaserin Second Study for Obesity Management) evaluated obese and overweight patients to demonstrate the efficacy of lorcaserin (10 mg twice daily) over placebo [83.84]
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