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10.1095/biolreprod.114.117911 10 ChambersG

Excess copper primarily exacerbates cognitive impairment by increasing the expression of amyloid precursor protein (APP) and -site APP cleaving enzyme 1 (BACE1), promoting the accumulation of amyloid (A) (73)

Chemosphere 58:11531159 Paetzold SC, Ross NW, Richards RC, Jones M, Hellou J, Bard SM (2009) Up-regulation of hepatic ABCC2, ABCG2, CYP1A1, and GST in multixenobiotic-resistant killifish ( Fundulus heteroclitus ) from the Sydney Tar Ponds, Nova Scotia, Canada

[DOI] [PMC free article] [PubMed] [Google Scholar] Liu L, Jia F, Yuan G, Chen Z, Yao J, Li H, Fang C (2010) Tyrosine hydroxylase, interleukin-1beta and tumor necrosis factor-alpha are overexpressed in peripheral blood mononuclear cells from schizophrenia patients as determined by semi-quantitative analysis

447,448 Similarly, in mouse models, the genetically engineered S