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In the context of metabolic disequilibrium, excessive lipid accumulation and mtROS activate the NLRP3 inflammasome in both hepatocytes and Kupffer cells
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Adrenal fatigue is a condition that occurs when prolonged stress overworks your adrenal glands, leading to a range of symptoms including hormone imbalances

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A consolidated summary of all extracted outcomes, population characteristics, and mechanistic insights is presented in Table 2 to facilitate comparison across studies