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As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Tilg et al., 2020)
Weight loss of 710% body weight can significantly reduce liver fat and inflammation in NAFLD

Crohns Colitis 16 , 224243 (2022)

Importantly, markers of neurogenesis have been reported in adult human brain specimens following stroke (Moreno-Jimnez et al., 2019)

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