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Pyruvate dehydrogenase complex deficiency due to primary-specific genes ( PDHA1 , PDHB , DLAT , PDHX , PDP1 , and PDK3 ) constitute 80% to 90% of all cases with pyruvate dehydrogenase complex deficiency (76

NGF, together with its receptors, is expressed in pancreatic tumours, which contribute to their survival, proliferation, invasion and metastasis 12,13,14,15

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