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Troubleshooting common issues Even with proper protocols, issues occasionally arise
Mice and humans that lack or overexpress MYOC have normal aqueous drainage and do not develop high IOP whereas mice expressing the human Tyr437His mutation in the olfactomedin domain develop elevated IOP and optic nerve damage that mirrors human glaucoma (21)
A similar observation has been cited earlier, where Salganik and peers experimentally revealed that dietary antioxidants had no impact on brain tumor growth, or could worsen the outcome [242]
Oral retinoids are forbidden during pregnancy because they may cause severe fetal malformations
Yin Y, Liu Z, Li Q, et al
